Can normal saline be given intramuscularly?

Abstract. Intramuscular injection of hypertonic saline (4-6% NaCl) is widely used to induce muscle pain in volunteers. The quality of the pain is comparable to clinical muscle pain with localised and referred pain.

How to use Normal Saline Flush Injection Syringe. This product is given by injection into the IV catheter as directed by your doctor. If you are using this product at home, learn all preparation and usage instructions from your health care professional.

The intramuscular route is used where effects are desired over a longer period of time than can be expected after intravenous injection, for drugs that are too irritant to be given subcutaneously, or for oily solutions, which cannot be given intravenously.

Sterile water for irrigation is NOT FDA labeled for any use as an injection in patients.

The most common medications given by IM route include:

• Antibiotics- penicillin G benzathine penicillin, streptomycin.
• Biologicals- immunoglobins, vaccines, and toxoids.
• Hormonal agents- testosterone, medroxyprogesterone[2]

When a person receives fluids intravenously (through an IV bag, for example), a saline solution is sometime used. Giving large amounts of pure water directly into a vein would cause your blood cells to become hypotonic, possibly leading to death.

Normal saline solution can be administered only Via intravenous (IV) access. 0.9% Normal Saline (NS, 0.9NaCl, or NSS) is one of the most common IV fluids, it is administered for most hydration needs: hemorrhage, vomiting, diarrhea, hemorrhage, drainage from GI suction, metabolic acidosis, or shock.

The IV group experienced a significantly faster onset of analgesic effect than the IM group (5 minutes versus 20 minutes). During 5–25 minutes after morphine administration, pain status in the IV group was significantly improved compared with the IM group.

IV infusions allow a set amount of medication to be administered in a controlled manner over a period of time. Intramuscular (IM) injections. IM injections are given deep into a muscle where the medication is then absorbed quickly by surrounding blood vessels.

A direct IV injection, or IV push, involves injecting a therapeutic dose of a medication or another substance directly into a vein. The benefit of a direct IV injection is that it Delivers the necessary dose of a drug very quickly, which helps it take effect as rapidly as possible.

Conclusion: Sterile water is an inexpensive alternative to isotonic saline for irrigation during PCNL. We did not find any difference between the two irrigation solutions regarding the safety; however, this should be confirmed further, especially for larger calculi.

0.9% Sodium Chloride Injection USP is indicated for Extracellular fluid replacement, treatment of metabolic alkalosis in the presence of fluid loss and mild sodium depletion.

The following are primary indications for the use of normal saline infusion that have been approved by the FDA:

1. Extracellular fluid replacement (e.g., dehydration, hypovolemia, hemorrhage, sepsis)
2. Treatment of metabolic alkalosis in the presence of fluid loss.
3. Mild sodium depletion.

Aspiration before injection of vaccines or toxoids (i.e., pulling back on the syringe plunger after needle insertion but before injection) is Not necessary Because no large blood vessels are present at the recommended injection sites, and a process that includes aspiration might be more painful for infants (22).

Aspiration is most commonly performed during an intramuscular (IM) or subcutaneous (SC) injection, and is meant to ensure that the needle tip is located at the desired site, and has not accidentally punctured a blood vessel.

If you see blood in the syringe, you have hit a blood vessel. If you hit a vessel, Pull the needle out of the skin. Get rid of the needle and syringe, and prepare a new syringe with medicine. Insert the new needle in a different spot, and check again to see if there is blood.

Administer via central line ONLY; give in small (e.g., 30 mL) infusion aliquots over 2 to 30 minutes. Rates can vary from 75 to 150 mL/hour (1 to 2 mL/kg/hour).

Sodium chloride 23.4% injection is used to Replenish lost water and salt in your body due to certain conditions (eg, hyponatremia or low salt syndrome). It is also used as an additive for total parenteral nutrition (TPN) and carbohydrate-containing IV fluids.

Normal saline is 0.9% sodium chloride. Hypertonic saline is 7.5% sodium chloride (eight times as concentrated as normal saline).

Eventhough IP administration of pharmacological agents results in faster and more complete absorption compared to oral, intramuscular and SC routes, this route as any other, has certain limitations.

Intramuscular injections are absorbed faster than subcutaneous injections. This is because muscle tissue has a greater blood supply than the tissue just under your skin. Muscle tissue can also hold a larger volume of medication than subcutaneous tissue.

For “deep” IM injections, the recommended volume ranges from 2 to 5 ml. If the patient’s available muscle tissue is limited and the dorsogluteal muscle must be used, volumes of up to 4 ml can be administered into this site. The ventrogluteal muscle can accommodate up to 2.5 ml, with a maximum volume of 3 ml.

Abbreviations: IV = intravenous, IM = intramuscular, SC = subcutaneous.